diff --git a/README.org b/README.org
index 51adda8..613db92 100644
--- a/README.org
+++ b/README.org
@@ -1713,7 +1713,8 @@ v org-latex-classes)}}} for an explanation of the code in listing
 
   (with-eval-after-load 'ob-python
     (custom-set-variables
-     '(org-babel-python-command "python3 -E")))
+     '(org-babel-python-command
+       "ipython3 --simple-prompt --HistoryAccessor.enabled=False")))
 #+end_src
 
 #+caption[Customize =ob-python=]:
@@ -3058,7 +3059,10 @@ of [[https://github.com/jorgenschaefer/pyvenv#readme][pyvenv]]).  Therefore, thi
   (with-eval-after-load 'python
     (custom-set-variables
      '(python-indent-guess-indent-offset nil)
-     '(python-shell-interpreter-args "-i -E")))
+     '(python-shell-completion-native-disabled-interpreters '("ipython3" "pypy"))
+     '(python-shell-interpreter "ipython3")
+     '(python-shell-interpreter-args
+       "--simple-prompt --HistoryAccessor.enabled=False")))
 #+end_src
 
 #+caption[Manage =pyenv=]: